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Postdoctoral Fellow - Parkinson's Pre-Clinical Model Systems - P. Brundin Lab

at Van Andel Institute

Posted: 5/25/2019
Job Reference #: 417
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Job Description

Tracking Code
417-085
Job Description

Postdoctoral Fellow - Pre-Clinical Model Systems in Parkinson's

Van Andel Research Institute’s P. Brundin Laboratory, under the direction of Patrik Brundin, M.D., Ph.D., has a position available for one Postdoctoral Fellow.

The Patrik Brundin lab focus on pathogenetic mechanisms and pharmacological treatment in cell and animal models of Parkinson's disease. They also study cell replacement therapy with stem cells in attempts to repair brains in animal models of parkinsonism. The group's mission is to understand neurodegenerative diseases and develop new therapies that are of benefit to patients and their caregivers.

Recently, the lab been involved in one of the most promising developments for a cure, or at least progress in fighting Parkinson’s disease. A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of the lab’s new research.

The postdoctoral position is available immediately and is for a motivated scientist who meets the qualifications and description outlined below. The fellow will investigate the contribution of alpha-synuclein to the pathophysiology of Parkinson’s disease in pre-clinical model systems.

Specifically, we are interested in candidates with a background in neuroscience and Parkinson’s disease.

Qualifications:

  • A Ph.D. or M.D./Ph.D. in neuroscience, biochemistry, and/or molecular and cell biology with expertise in Parkinson’s disease.
  • Experience with mouse models of neurological disease and knowledge of brain morphology are expected.
  • Previous experience with molecular and cell biology techniques, stereotaxic surgery, and mouse behavioral studies are also expected.
  • A strong record of high-impact peer-reviewed publications is highly desirable.
  • Must provide the names of three individuals who can provide recommendations and present a scientific seminar describing his or her previous research.

Description of a Successful Candidate:

  • A self-motivated and driven individual who is able to exhibit exceptional research productivity and take responsibility for independent management of the project.
  • A detail-oriented researcher that thinks critically to effectively design experiments and solve complex research problems.
  • A strong ability to take initiative and work independently, as well as in a team environment.
  • A collaborative, hands-on researcher who proactively shares knowledge and expertise with lab members.
  • Excellent written and oral communication skills.

Job Functions:

This project is NIH Funded (R01) and the overall goal of the project is to study the contribution of alpha-synuclein to Parkinson’s disease. The candidate will use established model systems to determine effects of alpha-synuclein pathology. The results from these studies could lead to development of novel therapeutic strategies to improve clinical outcomes of Parkinson’s disease. While working with Dr. Brundin and his research team, the candidate will help guide research directions and provide expertise to facilitate the highest level of contribution to reach the project objectives.

Van Andel Research Institute (VARI) provides postdoctoral training opportunities to scientists beginning their research careers. The fellowships are to help promising scientists advance their knowledge and research experience and at the same time support the research endeavors of VARI under the mentorship of a VARI Faculty member.

While this project is currently funded, an integral part of postdoctoral training is the process of preparing a research proposal and writing a fellowship application. All VARI Postdoctoral Fellows are encouraged to apply for external funding as soon as it is practical and reasonable after hire. Receiving a fellowship award provides recognition for both the fellow and VARI!

Application Process:

Qualified applicants should APPLY ONLINE and provide a cover letter outlining research experience and interests, a curriculum vitae, and the names and address of three references.

If you possess these attributes and desire to help us drive science from the bench to the clinic; while benefiting from a highly generous compensation package; we would welcome speaking with you and encourage you to APPLY TODAY.

VAI is actively striving to diversify its workforce and strongly encourages qualified individuals from underrepresented groups to apply. Van Andel Institute is an EEO and Affirmative Action Employer.

This position will be open until filled. If you have any difficulty uploading your application or any questions, please email Eric Miller at eric.miller@vai.org.

About Grand Rapids, MI

Van Andel Research Institute is located in downtown Grand Rapids, MI which is the second largest city in Michigan and the largest city in West Michigan. Grand Rapids offers a remarkable combination of cosmopolitan atmosphere and small town warmth, known for its philanthropic and sustainability-driven community, and is ranked one of "America's Top 100 Places to Live."

Located on the banks of the Grand River, Grand Rapids offers all the big-city excitement you'd expect from a million-resident metropolis, featuring hundreds of restaurants and nightspots, theaters, museums, sports and concerts. The safe and clean downtown is surrounded by an eclectic mix of walk-able neighborhoods.



With a medical and life sciences industry boom, strong entrepreneurial activity, dedication to green building and living, and innovative employers, Grand Rapids' diverse economy continues to grow, offering endless career opportunities.

Job Location
Grand Rapids, Michigan, United States
Position Type
Full-Time/Regular